L’Oreal For Women in Science Malaysia 2024 winner Dr Wong Sok Kuan is revolutionising osteoporosis treatments—merging science and collaboration to tackle complex healthcare challenges
The most remarkable careers often begin with unplanned detours. For Dr Wong Sok Kuan, scientific research wasn’t the intended destination.
“I actually never planned on a career in scientific research,” says the assistant professor at Universiti Kebangsaan Malaysia’s (UKM) Department of Pharmacology. But hands-on exposure during her biochemistry studies changed everything. What started as curiosity evolved into a passion for probing the molecular mechanisms of human health. “I saw firsthand how even small breakthroughs in the lab could eventually translate into real-world benefits, and that realisation motivated me to pursue a PhD and delve deeper into biomedical research.”
As each experiment revealed new possibilities in metabolic disorders and bone health, Wong was determined to use science-based solutions to address complex healthcare challenges. Now, as a L’Oréal-UNESCO For Women in Science Malaysia 2024 awardee, her pioneering work is set to transform the way we understand and treat diabetes-induced osteoporosis.
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At the heart of Wong’s research lies an ambitious goal: redefining how diabetes-related bone loss is treated. “Right now, diabetes and osteoporosis are managed separately with medications targeting each condition,” she explains. “By targeting Glycogen Synthase Kinase-3 Beta (GSK3), we’re looking at a potential ‘master switch’ that regulates inflammation, connecting blood glucose control and bone metabolism.”
This approach could lead to earlier diagnosis and more effective treatments, tackling not just bone loss but the root causes linked to insulin resistance and inflammation. From fewer fractures and lower healthcare costs to an improved quality of life for Malaysia’s ageing population, the impact of this could be profound.